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Journal of the Korean Child Neurology Society 2005;13(2):294-298.
Published online November 30, 2005.
A Case of Basal Ganglia Germinoma Presenting Only with Cerebral Hemiatrophy Diagnosed by Using 11C-Methionine Positron Emission Tomography.
Jeehun Lee, Kye Hyang Lee, Jung Min Suh, Byung Tae Kim, Heong Jin Shin, Ji Hye Kim, Yeon Lim Suh, Munhyang Lee
1Department of Pediatrics, Sungkyunkwan University, School of Medicine, Seoul, Korea. mhlee@samsung.co.kr
2Department of Nuclear Medicine, Sungkyunkwan University, School of Medicine, Seoul, Korea.
3Department of Neurosurgery, Sungkyunkwan University, School of Medicine, Seoul, Korea.
4Department of Radiology and Center for Imaging Science, Sungkyunkwan University, School of Medicine, Seoul, Korea.
5Department of Pathology, Samsung Medical Center, Sungkyunkwan University, School of Medicine, Seoul, Korea.
We present a case of cerebral germinoma that occurred in the basal ganglia with progressive hemiparesis. A 10-year-old boy was referred to our hospital complaining of progressive right hemiparesis and decreased mental functions. Brain MRI showed left cerebral hemiatrophy and high signal intensity in left thalamus, basal ganglia, cerebral peduncle, and pons. However, no mass or enhancement was observed. 11C-Methionine positron emission tomography showed discernable hot uptake in the left basal ganglia and thalamus. Stereotactic biopsy, with a guide of 11C-Methionine positron emission tomography, was performed and the diagnosis of pure germ cell tumor was determined. 11C-Methionine positron emission tomography is useful for localization of a suspicious tumor in patients with cerebral hemiatrophy without overt mass or enhancing lesions in brain MRI.
Key Words: 11C-methionine positron emission tomography, Germinoma, Basal ganglia, Cerebral hemiatrophy
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