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Journal of the Korean Child Neurology Society 2007;15(2):179-184.
Published online November 30, 2007.
Moyamoya Disease in Children and Adolescents.
Seung Ik Lee, Geun Ha Chi, Tae Gyu Hwang
Department of Pediatrics, School of Medicine, Inje University, Busan, Korea. htg6700@chollian.net
Abstract
PURPOSE
Moyamoya disease is a chronic cerebrovascular illness characterized by bilateral stenoses or occlusions of the arteries around the circle of Willis with prominent collateral circulation. We studied 36 children and adolescents with Moyamoya disease to evaluate the clinical features and outcomes. METHODS: Records were reviewed of 36 pediatric patients admitted at the Busan Paik Hospital for Moyamoya disease between January 2000 and July 2007. The clinical records were reviewed in terms of the patient profiles, imaging findings, surgical techniques, and pathologic findings. RESULTS: Overall clinical features, responses to treatment and outcome were nearly same as those of other previous reports in Korea as well as the other countries. The mean age of onset was 8 years and 5 months and the ratio of male to female was 1:1.2. Ischemia was more often than infarction(5.6: 1). Half of the patients had conservative therapy and 17 cases(47%) were treated with EDAS. CONCLUSION: The clinical features of childhood Moyamoya disease are similar to the result from other studies in Korea.
Key Words: Childhood Moyamoya disease, Clinical features


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