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Journal of the Korean Child Neurology Society 2002;10(2):314-324.
Published online November 30, 2002.
The Cases of Surgical Treatment of Intractable Childhood Epilepsy with Tuberous Sclerosis.
Da Eun Jung, Jung Chae Park, Hee Jung Chung, Hoon Chul Kang, Heung Dong Kim, Yong Soon Hwang
1Epileptic Center, Inje University, College of Medicine, Sang-Gye Paik Hospital, Seoul, Korea. hdkimmd@sanggyepaik.ac.kr
2Department of Pediatrics, Inje University, College of Medicine, Sang-Gye Paik Hospital, Seoul, Korea.
3Department of Neurosurgery, Inje University, College of Medicine, Sang-Gye Paik Hospital, Seoul, Korea.
4Sowha Children's Hospital, Seoul, Korea.
5National Health Insurance Corporation, Ilsan Hospital, Ilsan, Korea.
Abstract
Tuberous sclerosis(TS) is a disorder of aberrant neuronal differentiation and proliferation manifesting as multiple central nervous system(CNS) hamartomas. Seizures in patients with TS are often intractable to anticonvulsant therapy. Although TS shows various lesions including multiple tubers, many patients with well localized epileptic focus to some tubers may have a benefit from epileptic surgery. We experienced three cases who had clinical improvement after epileptic surgery in intractable epilepsy complicated by TS. We report three cases and the brief review of literatures.
Key Words: Tuberous sclerosis, Epileptic surgery


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