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Journal of the Korean Child Neurology Society 2010;18(1):108-111.
Published online May 30, 2010.
Guillain-Barre Syndrome Caused by Swine Influenza(H1N1) Vaccination: A Case Report.
Yong Jae Park, Eun Sook Suh
Department of Pediatrics, College of Medicine, Soonchunhyang University, Seoul, Korea. essuh@hosp.sch.ac.kr
Abstract
Guillain-Barre syndrome(GBS), characterized by Landry's ascending paralysis, has been known to be caused by some viruses and some vaccinations. We report a case of GBS caused by swine influenza vaccination. The patient presented with rapidly progressive ascending paralysis after vaccination. After intravenous immunoglobulin therapy and other conservative treatments, he recovered without any complications. Whilst the patient did not exhibit typical GBS features, we still suspect that this case represents a variant of GBS. GBS secondary to vaccination is rare and the association has yet to be proven. We therefore recommend that swine influenza vaccination continue despite this apparent case of secondary GBS.
Key Words: Influenza A virus, H1N1 subtype
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