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Journal of the Korean Child Neurology Society 2010;18(2):311-316.
Published online November 30, 2010.
A Case of Atypical Miller-Fisher Syndrome with Internal Carotid Artery Stenosis.
Ji Hoon Jin, Eun Hye Choi, Sung Dae Cho, Byong Kwan Son, Sung Mo Kang, Young Se Kwon
1Department of Pediatrics, College of Medicine, Inha University, Korea. ysped@inha.ac.kr
2Department of Ophthalmology, College of Medicine, Inha University, Korea.
Abstract
Miller-Fisher syndrome is an acute poly-neuropathy typically characterized by the triad of ophthalmoplegia, ataxia, and areflexia. Other poly-neuropathy diseases include Guillain-Barre syndrome and Bickerstaff brainstem encephalitis. However, not all cases of Miller-Fisher syndrome have the typical three symptoms. These diseases have been differentiated by clinical manifestations and anti-GQ1b IgG antibody testing. In Miller-Fisher syndrome, anti-GQ1b IgG antibody is present in over 95% of patients; however, the frequency is not so high in normal subjects or in those with other poly-neuropathy diseases. Infectious illnesses, such as respiratory diseases and gastrointestinal diseases, usually precede Miller-Fisher syndrome. In general, Miller-Fisher syndrome is a self-limiting illness; however, a few cases of Miller-Fisher syndrome progressing to respiratory failure have been reported, particularly in children. In this case, we report abnormal angiographic findings. We report a case of atypical Miller-Fisher syndrome with internal carotid artery stenosis treated with prednisolone.
Key Words: Miller Fisher Syndrome, Polyneuropathies, Child, Vascular stenosis


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