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Ann Child Neurol > Volume 26(2); 2018 > Article
Journal of the Korean Child Neurology Society 2018;26(2):119-122.
DOI: https://doi.org/10.26815/jkcns.2018.26.2.119    Published online June 30, 2018.
A Child with Mycoplasma pneumoniae-related Encephalitis Presenting as Hyperactive Behavior Change.
Hyo Bin Kim, So Myung Kong, Jin Sung Park, Su Jeong You
1Department of Pediatrics, Inje University Sanggye Paik Hospital, Seoul, Korea. su6236@naver.com
2Department of Pediatrics, Kangwon National University Hospital, Chuncheon-Si, Korea.
Mycoplasma pneumoniae is a respiratory pathogen responsible for various upper and lower respiratory tract diseases. This also induces extra-pulmonary manifestations, with encephalitis being the most frequent and critical manifestation in pediatric populations. This report describes an 8-year-old boy who presented with repetitive motions in both hands, agitation, muttering and increased appetite after seizure. He had started treatment with antibiotics for M. pneumoniae infection 14 days prior to this event. Electroencephalography (EEG) showed slow and disorganized background rhythms and polymorphic slowing on both frontal areas, whereas brain magnetic resonance imaging was normal. He was diagnosed with M. pneumoniae-related encephalitis and treated with intravenous immunoglobulin (500 mg/kg/day for 4 days). After 3 days, his impulsive behaviors disappeared and, after 4 days, his EEG became normal. Abrupt hyperactive behavior in children may be a sign of M. pneumoniae-related encephalitis.
Key Words: Mycoplasma pneumoniae, Encephalitis, Hyperactive behavior, Autoimmune


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