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Journal of the Korean Child Neurology Society 2003;11(2):351-355.
Published online November 30, 2003.
A Case of Relapsing Acute Necrotizing Encephalopathy.
Jong Seo Yoon, So Hyun Park, Dong Un Kim, Young Hoon Kim, Jin Lee, Pil Sang Jang, Jin Tack Kim, Kyung Tai Whang
Department of Pediatrics, College of Medicine, The Catholic University of Korea, Seoul, Korea. pedkyh@catholic.ac.kr
Abstract
A 4-year-old boy showed two episodes of encephalitis/encephalopathy involving disturbed consciousness, convulsion, and paresis associated with the elevated levels of protein and no pleocytosis of the cerebrospinal fluid. MRI studies of the brain revealed symmetrical lesions in the brain stem and thalamus at the first episode, and their sizes were regressed. The lesions were enlarged to the previous size in the second episode. These episodes were not followed by an elevation of the anti-viral antibody titer. In the second episode, intravenous methylprednisolone therapy and intravenous immunoglobulin therapy were introduced.
Key Words: Acute necrotizing encephalopathy, Relapsing


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